Primary Identifier | MGI:2139469 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 380601 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable rRNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and nose. Orthologous to human FASTKD5 (FAST kinase domains 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |