| Primary Identifier | MGI:1341873 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 14588 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glial cell-derived neurotrophic factor receptor activity. Acts upstream of or within negative regulation of ossification. Predicted to be located in extracellular space. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including brain; endocrine gland; ganglia; spinal cord; and testis. Orthologous to human GFRA4 (GDNF family receptor alpha 4). PHENOTYPE: Homozygotes for targeted null mutations are mice were viable, fertile, showed no overt anatomical defects. Thyroid tissue calcitonin content was reduced in null homozygotes and rate of bone formation was enhanced when in 129/B6 hybrid background strain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
