Primary Identifier | MGI:2442060 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 215653 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase activity. Acts upstream of or within several processes, including canonical NF-kappaB signal transduction; negative regulation of non-canonical NF-kappaB signal transduction; and regulation of osteoclast differentiation. Located in cytoplasm and nucleus. Is expressed in central nervous system; heart valve; and urinary system. Orthologous to human RASSF2 (Ras association domain family member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit bone defects and hematopoeitic abnormalities. [provided by MGI curators] |