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Protein Coding Gene : Trmt6 tRNA methyltransferase 6
Primary Identifier  MGI:1914176 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66926
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in mRNA processing. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Is expressed in brain ventricular layer; cerebral cortex subventricular zone; olfactory epithelium; submandibular gland primordium; and thymus primordium. Orthologous to human TRMT6 (tRNA methyltransferase 6 non-catalytic subunit).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased CD4+ T cells and stimulated T cell proliferation. [provided by MGI curators]
  • synonyms:
  • MGI:2139353,
  • AW492787,
  • mKIAA1153,
  • expressed sequence AU016412,
  • MGI:2139161,
  • expressed sequence AW492787,
  • tRNA methyltransferase 6,
  • Trmt6,
  • RIKEN cDNA 3300001M20 gene,
  • 3300001M20Rik,
  • AU016412
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2 Involved In Mutations

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Canonical gene --> Exons in specific strains

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