| Primary Identifier | MGI:1913836 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 66586 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cardiolipin synthase (CMP-forming). Predicted to be involved in cardiolipin biosynthetic process; response to phosphatidylethanolamine; and response to thyroxine. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 57. Orthologous to human CRLS1 (cardiolipin synthase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit defects in chorion and trophoblast layer formation and complete lethality throughout fetal growth and development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
