| Primary Identifier | MGI:107464 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 18798 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mitogen-activated protein kinase binding activity and phosphatidylinositol phospholipase C activity. Involved in modulation of chemical synaptic transmission. Located in several cellular components, including dendrite; postsynaptic density; and smooth endoplasmic reticulum. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and postsynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLCB4 (phospholipase C beta 4). PHENOTYPE: Homozygotes for targeted mutations may exhibit ataxia, impaired elimination of excess climbing fiber synapses in the developing cerebellum, abnormal cerebellar foliation, reduced visual processing ability and loss of circadian rhythm in constant darkness. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
