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Protein Coding Gene : Lamp5 lysosomal-associated membrane protein family, member 5
Primary Identifier  MGI:1923411 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  76161
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in presynaptic modulation of chemical synaptic transmission. Located in several cellular components, including dendrite membrane; endosome; and growth cone membrane. Is active in GABA-ergic synapse and synaptic vesicle. Is expressed in several structures, including alimentary system; central nervous system; sensory organ; vertebral axis musculature; and vibrissa. Orthologous to human LAMP5 (lysosomal associated membrane protein family member 5).
PHENOTYPE: Homozygous null mice show increased susceptibility to PTZ-induced seizures, distinct interneuron loss, dystrophic neurites, delayed habituation in the open field and neuronal network deficits. [provided by MGI curators]
  • synonyms:
  • lysosomal-associated membrane protein family, member 5,
  • RIKEN cDNA 6330527O06 gene,
  • RIKEN cDNA 3110035N03 gene,
  • MGI:1920368,
  • BAD-LAMP,
  • 6330527O06Rik,
  • Lamp5,
  • 3110035N03Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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3 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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2 Driver For





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