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Protein Coding Gene : Pak5 p21 (RAC1) activated kinase 5

Primary Identifier  MGI:1920334 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  241656
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein serine/threonine kinase activity. Acts upstream of or within learning or memory; locomotory behavior; and negative regulation of extrinsic apoptotic signaling pathway. Located in mitochondrion. Is active in synapse. Is expressed in brain and sciatic nerve. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5).
PHENOTYPE: Homozygous null mice exhibit impaired active avoidance learning but are otherwise normal. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2900083L08 gene,
  • 2900083L08Rik,
  • MGI:6436713,
  • p21 (RAC1) activated kinase 5,
  • Pak5,
  • p21 (RAC1) activated kinase 7,
  • p21 protein (Cdc42/Rac)-activated kinase 7,
  • Pak7

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For