Primary Identifier | MGI:1920149 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 72899 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ADP-ribosylglutamate hydrolase activity and deacetylase activity. Involved in brain development. Acts upstream of or within response to bacterium. Predicted to be located in nucleolus. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; muscle tissue; and sensory organ. Orthologous to human MACROD2 (mono-ADP ribosylhydrolase 2). PHENOTYPE: Mice homozygous for a knock-out allele are viable, healthy and overtly normal and show no significant changes in irradiation-induced lethality, high fat diet-induced obesity, or response to glucose or insulin challenge relative to wild-type controls. [provided by MGI curators] |