Primary Identifier | MGI:1098240 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 16558 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables small GTPase binding activity. Involved in several processes, including Golgi to endosome transport; endoderm development; and fibroblast growth factor receptor signaling pathway. Acts upstream of or within cellular response to type II interferon. Located in phagocytic vesicle. Orthologous to human KIF16B (kinesin family member 16B). PHENOTYPE: Chimera embryos containing a knock-out allele and derived from tetraploid rescue exhibit lethal growth arrest at the blastocyst stage with abnormal development of the primitive endoderm, epiblast epithelium, and basement membrane. [provided by MGI curators] |