| Primary Identifier | MGI:1298217 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13011 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine-type endopeptidase inhibitor activity. Involved in negative regulation of peptidase activity. Acts upstream of or within inhibition of cysteine-type endopeptidase activity; negative regulation of microglial cell activation; and positive regulation of myelination. Located in several cellular components, including Golgi apparatus; late endosome; and lysosome. Is expressed in several structures, including early conceptus and female reproductive system. Orthologous to human CST7 (cystatin F). PHENOTYPE: Mice homozygous for a null mutation display eosinophil granule abnormalities, increased eosinophil turnover, and impaired clearance of parasitic infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
