Primary Identifier | MGI:1919131 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 71881 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable arylesterase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cell surface and membrane. Is expressed in olfactory epithelium. Orthologous to human APMAP (adipocyte plasma membrane associated protein). PHENOTYPE: Homozygotes for a null allele show spatial memory deficits. Under a high-fat diet, homozygous deletion of exon 1 results in increased insulin sensitivity, improved glucose tolerance, increased respiratory exchange ratio, decreased inflammatory marker gene expression, and reduced adipocyte size. [provided by MGI curators] |