Primary Identifier | MGI:3652039 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 668929 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity. Acts upstream of or within several processes, including double-strand break repair via homologous recombination; homologous chromosome segregation; and seminiferous tubule development. Located in lateral element. Part of meiotic cohesin complex. Is expressed in brain; gonad; and metanephros. Orthologous to human RAD21L1 (RAD21 cohesin complex component like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility and reduced female fertility associated with abnormal meiosis and synaptonemal complex. [provided by MGI curators] |