Primary Identifier | MGI:1346072 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228769 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable proteasome binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in negative regulation of proteasomal protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol; endoplasmic reticulum; and perinuclear region of cytoplasm. Predicted to be part of proteasome complex. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver and biliary system; and nervous system. Orthologous to human PSMF1 (proteasome inhibitor subunit 1). PHENOTYPE: Mice homozygous for a null allele die perinatally and are small by E15.5. [provided by MGI curators] |