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Protein Coding Gene : Srxn1 sulfiredoxin 1 homolog (S. cerevisiae)
Primary Identifier  MGI:104971 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  76650
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables oxidoreductase activity, acting on a sulfur group of donors. Involved in response to oxidative stress. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in adrenal medulla and embryo. Orthologous to human SRXN1 (sulfiredoxin 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased sensitivity to LPS-induced shock. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI854065,
  • MGI:1923900,
  • MGI:2139100,
  • neoplastic progression 3,
  • sulfiredoxin 1 homolog (S. cerevisiae),
  • MGD-MRK-31044,
  • Npn3,
  • MGI:2139350,
  • RIKEN cDNA 1700127B04 gene,
  • AI854065,
  • 1700127B04Rik,
  • expressed sequence AW488194,
  • Srx1,
  • AW488194,
  • Srxn1,
  • Srx
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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Genes --> Homologs

Interactions

6 Pathways

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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