| Primary Identifier | MGI:88543 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 12995 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta-catenin binding activity; kinase activity; and protein phosphatase regulator activity. Acts upstream of or within protein autophosphorylation. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of PcG protein complex; Sin3-type complex; and protein kinase CK2 complex. Predicted to be active in PML body and cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1). PHENOTYPE: Mice homozygous for the null in the major catalytic subunit die by E11.5 and exhibit defects in neural, cardiac and limb development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
