Primary Identifier | MGI:1915167 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 67917 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; defense response to virus; and positive regulation of type I interferon production. Predicted to be active in cytoplasm. Is expressed in Meckel's cartilage; medulla oblongata basal plate mantle layer; skeleton; and ventral grey horn. Orthologous to human ZCCHC3 (zinc finger CCHC-type containing 3). PHENOTYPE: Mice homozygous for a knock-out allele are more susceptible to lethal infection by DNA viruses. [provided by MGI curators] |