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Protein Coding Gene : H13 histocompatibility 13
Primary Identifier  MGI:95886 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  14950
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable aspartic endopeptidase activity, intramembrane cleaving; protein homodimerization activity; and ubiquitin protein ligase binding activity. Acts upstream of or within in utero embryonic development. Located in cell surface and endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; embryo ectoderm; extraembryonic component; and musculoskeletal system. Orthologous to human HM13 (histocompatibility minor 13).
PHENOTYPE: This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele. [provided by MGI curators]
  • synonyms:
  • expressed sequence AV020344,
  • Hm13,
  • 5031424B04Rik,
  • histocompatibility 13,
  • RIKEN cDNA 1200006O09 gene,
  • MGI:1915400,
  • MGI:2139237,
  • MGD-MRK-10481,
  • MGI:2447815,
  • H13,
  • AV020344,
  • 4930443L17Rik,
  • RIKEN cDNA 4930443L17 gene,
  • MGI:1914866,
  • 1200006O09Rik,
  • Spp,
  • RIKEN cDNA 5031424B04 gene,
  • H-13,
  • MGD-MRK-10359
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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