Primary Identifier | MGI:2135755 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 84682 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrial membrane. Is expressed in several structures, including alimentary system; cardiovascular system; hindlimb musculature; nervous system; and sensory organ. Orthologous to human COX4I2 (cytochrome c oxidase subunit 4I2). PHENOTYPE: Mice homozygous for a null mutation display lung inflammation and decreased airway responsiveness. Females show decreased lean body mass and improved glucose tolerance. [provided by MGI curators] |