Primary Identifier | MGI:2385159 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228788 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including heart development; negative regulation of homotypic cell-cell adhesion; and positive regulation of fibroblast growth factor production. Is expressed in several structures, including cardiovascular system; genitourinary system; immune system; liver; and retina blood vessel. Orthologous to human CCM2L (CCM2 like scaffold protein). PHENOTYPE: Mice homozygous for a reporter allele exhibit delayed wound healing and show impaired tumor growth, poor tumor vascularization, and decreased metastatic potential following injection of Lewis Lung Carcinoma (LLC) cells. [provided by MGI curators] |