Primary Identifier | MGI:1933165 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 54711 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including chylomicron assembly; positive regulation of intrinsic apoptotic signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and sensory organ. Orthologous to human PLAGL2 (PLAG1 like zinc finger 2). PHENOTYPE: Mice homozygous for a null allele exhibit postnatal death due to a failure to absorb lipids in the intestine and other organs. [provided by MGI curators] |