Primary Identifier | MGI:2137431 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228801 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipid binding activity. Predicted to be involved in innate immune response in mucosa and negative regulation of toll-like receptor 4 signaling pathway. Predicted to be located in extracellular region. Is expressed in alimentary system; male reproductive gland or organ; primitive streak; respiratory system; and thymus. Orthologous to human BPIFB1 (BPI fold containing family B member 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit strain background sensitive transmission ratio distortion and increased basal MUC5B production. [provided by MGI curators] |