Primary Identifier | MGI:1914454 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 67204 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity; translation initiation factor activity; and translation initiation factor binding activity. Acts upstream of or within in utero embryonic development; male germ cell proliferation; and male gonad development. Is active in synapse. Is expressed in several structures, including blastocyst; colon; early embryo; gonad; and liver. Orthologous to human EIF2S2 (eukaryotic translation initiation factor 2 subunit beta). PHENOTYPE: Mice homozygous for a gene trap allele exhibit embryonic lethallity prior to E8.5. Mice heterozygous for a gene trap allele exhibit reduced incidence of testicular germ cell tumors. [provided by MGI curators] |