| Primary Identifier | MGI:1341867 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 17391 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cadherin binding activity and metalloendopeptidase activity. Involved in several processes, including cell-cell adhesion mediated by cadherin; detection of temperature stimulus involved in sensory perception of pain; and neuronal stem cell population maintenance. Located in plasma membrane and trans-Golgi network membrane. Is expressed in several structures, including eye; nervous system; and testis. Orthologous to human MMP24 (matrix metallopeptidase 24). PHENOTYPE: Mice homozygous for disruptions in this gene fail to develop neuropathic pain after peripheral nerve injury. They also experience reduced stress and enhanced mechanical coordination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
