| Primary Identifier | MGI:1196288 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 16418 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ribosomal large subunit binding activity. Involved in several processes, including regulation of megakaryocyte differentiation; regulation of primary metabolic process; and response to insulin. Located in lamin filament. Is active in synapse. Is expressed in cerebral cortex ventricular layer and liver. Orthologous to human EIF6 (eukaryotic translation initiation factor 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality prior to E3.5 and mice heterozygous for the allele exhibit reduced body, liver and adipose tissue weights associated with a reduced translation rate and delayed G1/S phase transition. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
