Primary Identifier | MGI:1915299 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 228839 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Acts upstream of or within several processes, including nodal signaling pathway; positive regulation of amacrine cell differentiation; and regulation of gastrulation. Predicted to be located in centrosome and nucleoplasm. Is expressed in several structures, including alimentary system; brain; forelimb phalanx; genitourinary system; and sensory organ. Orthologous to human TGIF2 (TGFB induced factor homeobox 2). PHENOTYPE: Homozygous mice are viable and do not display any gross defects. [provided by MGI curators] |