Primary Identifier | MGI:1922675 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 75425 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in positive regulation of DNA damage checkpoint and regulation of TOR signaling. Predicted to be part of TORC1 complex; TORC2 complex; and TTT Hsp90 cochaperone complex. Predicted to be active in cytoplasm. Orthologous to human TTI1 (TELO2 interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation. In vitro, blastocysts hatch from the zona pellucida and form typical outgrowth colonies after 3 days in culture. [provided by MGI curators] |