| Primary Identifier | MGI:3045315 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 329547 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in several processes, including defense response to other organism; lipopolysaccharide-mediated signaling pathway; and negative regulation of cytokine production. Located in cytoplasm. Human ortholog(s) of this gene implicated in Crohn's disease. Orthologous to human BPI (bactericidal permeability increasing protein). PHENOTYPE: Mice homozygous for a null allele display increased susceptibility to induced colitis and impaired IL22 induction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
