Primary Identifier | MGI:2675492 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 246747 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including brown fat cell differentiation; positive regulation of fat cell differentiation; and white fat cell differentiation. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in gut and male reproductive gland or organ. Orthologous to human ADIG (adipogenin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced high fat diet-induced fat and weight gain, decreased fat mass-adjusted leptin levels, and reduced leptin secretion in adipose explants. [provided by MGI curators] |