Primary Identifier | MGI:1922908 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 381404 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Acts upstream of or within RNA metabolic process; nucleus localization; and oocyte maturation. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Is expressed in early conceptus and gonad. Orthologous to human PABPC1L (poly(A) binding protein cytoplasmic 1 like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired oocyte maturation and female infertility. [provided by MGI curators] |