| Primary Identifier | MGI:1349164 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 20971 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including fibronectin binding activity; protein kinase C binding activity; and thrombospondin receptor activity. Involved in regulation of fibroblast migration. Acts upstream of or within inner ear receptor cell stereocilium organization; neural tube closure; and wound healing. Located in cell surface. Is expressed in several structures, including alimentary system; brain; genitourinary system; skeleton; and skin. Orthologous to human SDC4 (syndecan 4). PHENOTYPE: Mice homozygous or heterozygous for a knock-out allele show delayed wound healing and impaired angiogenesis. Homozygotes for a different knock-out allele exhibit degenerated fetal vessels in the placental labyrinth, abnormal cell adhesion, and high susceptibility to induced renal and hepatic injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
