| Primary Identifier | MGI:2385165 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 228869 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Acts upstream of or within glucose homeostasis and negative regulation of insulin receptor signaling pathway. Predicted to be located in actin cytoskeleton. Predicted to be active in nucleoplasm. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; immune system; and nervous system. Orthologous to human NCOA5 (nuclear receptor coactivator 5). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit impaired glucose homeostasis, liver dysplasia, increased hepatocellular carcinoma incidence, and male infertility associated with abnormal sperm motility, progression and morphology and increased IL-6 expression in the epididymis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
