Primary Identifier | MGI:1338864 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20853 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Involved in dendritic transport of messenger ribonucleoprotein complex. Acts upstream of or within intracellular mRNA localization. Located in cytoplasmic stress granule and neuron projection. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; gonad; and sensory organ. Orthologous to human STAU1 (staufen double-stranded RNA binding protein 1). PHENOTYPE: Mice homozygous for a targeted allele exhibit hypoactivity and impaired dendrite outgrowth and spine formation. [provided by MGI curators] |