Primary Identifier | MGI:1924210 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 76960 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Involved in myelination. Predicted to be located in cytosol. Predicted to be active in synapse. Orthologous to human BCAS1 (brain enriched myelin associated protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit hypomyelination, decreased prepulse inhibition suggestive of schizophrenia-like symptoms, a tendency toward reduced anxiety-like behaviors, and upregulation of inflammation-related genes in the brain. [provided by MGI curators] |