Primary Identifier | MGI:1914267 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 67017 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including erythrocyte differentiation; reactive oxygen species metabolic process; and spleen development. Is active in mitochondrion. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study systemic lupus erythematosus. Orthologous to human FAM210B (family with sequence similarity 210 member B). PHENOTYPE: Mice homozygous for a null mutation display a low incidence of increased autoantibody levels, splenomegaly, skin ulcers, and impaired erythocyte differentiation. [provided by MGI curators] |