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Protein Coding Gene : Rtf2 replication termination factor 2
Primary Identifier  MGI:1913654 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66404
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA binding activity. Predicted to be involved in cellular response to hydroxyurea and regulation of DNA stability. Predicted to be located in replication fork. Predicted to be active in nucleus. Is expressed in embryo. Orthologous to human RTF2 (replication termination factor 2).
PHENOTYPE: Mice homozygous for a null allele display embryonic lethality. Null MEFs display decreased DNA replication and slowed proliferation. [provided by MGI curators]
  • synonyms:
  • 1700067C04Rik,
  • RIKEN cDNA 2410001C21 gene,
  • RIKEN cDNA 1700067C04 gene,
  • RIKEN cDNA 5730427M17 gene,
  • MGI:1921524,
  • Rtf2,
  • 2410001C21Rik,
  • Rtfdc1,
  • 5730427M17Rik,
  • MGI:2138797,
  • MGI:6107623,
  • expressed sequence AA589417,
  • replication termination factor 2 domain containing 1,
  • AA589417,
  • replication termination factor 2
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