Primary Identifier | MGI:1861674 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 56802 |
Mgi Type | antisense lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including genomic imprinting; skin development; and tissue homeostasis. Is expressed in several structures, including brain; limb; and somite. Used to study pseudohypoparathyroidism. Human ortholog(s) of this gene implicated in pseudohypoparathyroidism type 1B. Orthologous to human GNAS-AS1 (GNAS antisense RNA 1). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit postnatal lethality, abnormal suckling, lethargy, decreased body size, and altered maternal imprinting. [provided by MGI curators] |