| Primary Identifier | MGI:1933281 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 320558 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Acts upstream of or within several processes, including male genitalia morphogenesis; meiotic nuclear division; and negative regulation of apoptotic process. Located in lateral element. Is expressed in meiotic germ cell of ovary; oocyte; primary oocyte; and spermatocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 1. Orthologous to human SYCP2 (synaptonemal complex protein 2). PHENOTYPE: Male mice homozygous for a knock-out allele are sterile due to lack of axial element formation and subsequent failure of chromosome synapsis in prophase I spermatocytes, while females are subfertile with a sharply reduced litter size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
