Primary Identifier | MGI:3040677 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241846 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Involved in several processes, including maternal mRNA clearance; meiotic cell cycle process involved in oocyte maturation; and ovarian follicle development. Located in cytoplasmic ribonucleoprotein granule. Is expressed in several structures, including early embryo; facial prominence; liver; oocyte; and spleen. Orthologous to human LSM14B (LSM family member 14B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female infertility and oocytes that are incompetent to complete meiosis and early embryogenesis. Male fertility is normal. [provided by MGI curators] |