Primary Identifier | MGI:2139279 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 99296 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable several functions, including G protein-coupled amine receptor activity; amine binding activity; and heterocyclic compound binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; learning or memory; and regulation of secretion. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in dendrite; plasma membrane; and synapse. Is expressed in brain. Orthologous to human HRH3 (histamine receptor H3). PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced locomotor activity and body temperature, and attenuated behavioral responses to the drugs thioperamide, methamphetamine, and scopolamine. [provided by MGI curators] |