Primary Identifier | MGI:97386 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 18216 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled neurotensin receptor activity and identical protein binding activity. Acts upstream of or within adult locomotory behavior. Predicted to be located in several cellular components, including dendrite; perikaryon; and symmetric synapse. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; eye; gallbladder; intestine; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human NTSR1 (neurotensin receptor 1). PHENOTYPE: Mice deficient for this marker have normal baseline prepulse inhibition responses and acoustic startle responses. Mice are heavier, eat more, and have lower body temperatures. [provided by MGI curators] |