| Primary Identifier | MGI:1344352 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 23856 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Acts upstream of or within apoptotic signaling pathway. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and spleen. Used to study myelodysplastic/myeloproliferative neoplasm. Orthologous to human DIDO1 (death inducer-obliterator 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit severely reduced fertility; about one-half develop a transplantable disease characterized by anomalies in spleen, bone marrow, and peripheral blood and including anemia and various symptoms typical of myeloid dysplasia or myeloid proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
