Primary Identifier | MGI:99683 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20459 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; non-membrane spanning protein tyrosine kinase activity; and signaling receptor binding activity. Involved in intestinal epithelial cell differentiation and negative regulation of growth. Located in nucleus. Is expressed in several structures, including gut; liver; and skin. Orthologous to human PTK6 (protein tyrosine kinase 6). PHENOTYPE: Mice homozygous for a null allele display increased villus length in the jejunum and ileum and increased villus epithelial cell proliferation. [provided by MGI curators] |