Primary Identifier | MGI:1353604 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 30942 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Acts upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in several cellular components, including intercellular bridge; mitotic spindle; and nucleoplasm. Predicted to be part of transcription regulator complex. Is expressed in several structures, including genitourinary system; gut; and nervous system. Orthologous to human HNF4G (hepatocyte nuclear factor 4 gamma). PHENOTYPE: Mice homozygous for a knock-out allele are less inclined to build nests, spend more time in a passive state during the forced swim test, and display a reduction in energy expenditure and night time activity that results in increased body weight despite adecreased intake of food and water. [provided by MGI curators] |