| Primary Identifier | MGI:1918850 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 229096 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable N6-methyladenosine-containing RNA reader activity; mRNA binding activity; and ribosome binding activity. Involved in mRNA destabilization and negative regulation of type I interferon-mediated signaling pathway. Located in cytoplasm. Is expressed in brain; cerebral cortex ventricular layer; cortical plate; intestine; and liver. Orthologous to human YTHDF3 (YTH N6-methyladenosine RNA binding protein F3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to vesicular stomatitis virus (VSV) infection. Homozygous KO does not affect viability or fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
