| Primary Identifier | MGI:3036269 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 381485 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; protein-macromolecule adaptor activity; and ubiquitin protein ligase activity. Acts upstream of or within with a positive effect on diapedesis and leukocyte migration involved in inflammatory response. Acts upstream of or within with a negative effect on macrophage migration. Predicted to be active in cytoplasm. Is expressed in cardiac muscle tissue; heart; heart left ventricle; and left atrium. Orthologous to human TRIM55 (tripartite motif containing 55). PHENOTYPE: Mice homozygous for a null allele exhibit increased heart and muscle to body weight ratios and cardiac hypertrophy. Homozygous mice exhibit reduced severity of symptoms following SARS coronavirus infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
