Primary Identifier | MGI:88479 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 12873 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallocarboxypeptidase activity. Involved in angiotensin maturation. Acts upstream of or within regulation of angiotensin levels in blood. Is active in extracellular region. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; retina; and skin. Orthologous to human CPA3 (carboxypeptidase A3). PHENOTYPE: Homozygous null mice have immature peritoneal mast cells but normal mast cell functions. [provided by MGI curators] |