| Primary Identifier | MGI:2441906 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 208188 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity; identical protein binding activity; and peptide hormone binding activity. Involved in adult feeding behavior and positive regulation of appetite. Acts upstream of or within several processes, including cellular response to insulin stimulus; growth hormone secretion; and positive regulation of insulin-like growth factor receptor signaling pathway. Predicted to be located in cell surface; membrane raft; and neuron projection. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; and trachea. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GHSR (growth hormone secretagogue receptor). PHENOTYPE: Homeostasis is disrupted by inactivation of this gene, namely growth hormone release and appetite stimulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
