| Primary Identifier | MGI:104860 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 14359 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR AU-rich region binding activity; molecular condensate scaffold activity; and ribonucleoprotein complex binding activity. Involved in several processes, including dentate gyrus development; modulation of chemical synaptic transmission; and regulation of gene expression. Located in several cellular components, including costamere; dendritic spine; and ribosome. Is active in several cellular components, including glutamatergic synapse; intracellular membraneless organelle; and postsynapse. Is expressed in several structures, including central nervous system; gut; heart; musculature; and sensory organ. Human ortholog(s) of this gene implicated in congenital myopathy 9A and congenital myopathy 9B. Orthologous to human FXR1 (FMR1 autosomal homolog 1). PHENOTYPE: Homozygous null mice display neonatal lethality with impaired muscle development. Mice homozygous for a hypomorphic allele display a reduced life span with impaired muscle development, growth retardation, and reduced grip strength. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
