Primary Identifier | MGI:108069 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 12428 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase binding activity. Acts upstream of or within positive regulation of DNA-templated transcription. Located in cytoplasm; female pronucleus; and male pronucleus. Part of cyclin A2-CDK1 complex and cyclin A2-CDK2 complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human CCNA2 (cyclin A2). PHENOTYPE: Embryos homozygous for a targeted mutation implant in the uterine wall, but fail to develop past 5.5 dpc. Notably, mutant embryos develop normally from the four-cell to the post-implantation stage in the absence of detectable maternally-derived gene products. [provided by MGI curators] |